In my last vacations, I went to my grandmother's house.

SMy grandmother is very affectionated and she is the person most important for me because she always helps you when you need it, she never willperson in my life. She always helps me in times of need, and I know that she will never leave youme alone.

I feel sad because I can't see her fam unable to see her as often or as lot of time or visited her many times, only onng as I like because I can only visit during my vacation ands. I miss her so much.

I hope to visited her soon.

InDuring my last vacations I went to my grandmother's house.

There are a few different ways you could start this
"During my last holidays"
"For my last holiday"
"During my last vacation"
They all have slightly different meanings, but nothing that matters too much. If it was a break from school or university in particular I would use holiday or holidays.

She is very affectionated and she is the person most important forto me because she always helps you when you need it,; she never will leave you alonr side.

"she never will leave you alone" has a negative connotation in English and makes it sound like your grandma is annoying. The above word choice is better.

I feel sad because I can't see her for a lot of timevery long or visited her many timesvery often, only onduring my vacation ands, I miss her so much.

This is more natural.

I hope to visited her soon.

Because you hope something will happen you cannot use the past tense because it has not happened yet.